2010年10月20日 星期三

A TECHNIQUE THAT SHOWS COLORFUL CONNECTIONS IN THE BRAIN

A TECHNIQUE THAT SHOWS COLORFUL CONNECTIONS IN THE BRAIN

The connections between neurons in a young, growing brain are more dynamic and changeable than previously thought,Every room stands to benefit from various light sources. This helps to create atmosphere. It also helps those who Insulator live there accomplished and complete tasks that require good light. according to research based on a new technique that reveals the brain circuitry of a living mouse.

A neuron looks a bit like a tree: its branches are dendrites,Like this, you can set table lamps a mood or read a book or sew with great ease. Remember that lots of lighting sources are necessary within any room. which accept input and its roots are the axon,Larger kitchens may require one or more ceiling fixtures positioned in the center of the room. Additional perimeter led tube squares or rectangles of lights placed near the walls should be installed for added illumination. These can be in the form of recessed downlight or track lighting. On the other hand, small kitchens may require only either two or three ceiling mounted fixtures or downlight placed near the walls. which send output. Where axons and dendrites of different neurons come together, they can make connections -- or synapses -- that relay signals and form circuits in the brain.

To study these connections, scientists have traditionally grown networks of neurons in petri dishes -- but there, networks are limited in their ability to mimic brain cells in a living, developing creature. Daniel Kerschensteiner, of Washington University School of Medicine in St. Louis, is one of the first to study connections in the nervous system of living mice, by inserting genes into neurons that cause them to produce fluorescent molecules.

"The novel thing is that we can label specific pairs of pre- and post-synaptic cells and their connections in an intact circuit," said Kerschensteiner. "No one has really done that before."

When energized by the imaging technique called two-photon microscopy, the molecules fluoresce in different colors and reveal the structure and connectivity of brain circuits.

This approach has already yielded some surprising insights. For instance, studies of the neurons in the mouse retina have shown that neural connections can change dramatically fairly late in an animal's development -- in its second week of life, long after the arrangement of axons and dendrites has already been laid down.And they should be balanced out throughout the space. Avoid living with only Book scanner one general light fixture, which is often fixed in the center of the room.

In ongoing experiments, Kerschensteiner hopes to further refine science's understanding of how a developing brain reorganizes its connections as it grows -- as well as the internal mechanisms behind this rearrangement and how much it is influenced by an animal's experiences and external environment.The task light should reach two-thirds of the counter. It is also important that the available compact fluorescent lighting will not shine people's eyes. You can avoid this by choosing shielded lights, or bulbs with mesh diffusers.

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