LOOKING FOR OSTEOPOROSIS WITH SCATTERED LIGHT
Researchers at the University of Rochester in New York are developing a new way to monitor bone health and search for signs of osteoporosis, using infrared light.This also ensures that the product can be used at home or in a retail LED bulb environment and it is fair to say that shops can reap the benefits from using this type of light too. At Frontiers in Optics 2010, Jason Maher, Andrew Berger, and their colleagues will present ongoing studies of the effects of steroids on the bones of mice.
Steroids are commonly prescribed for the treatment of rheumatoid arthritis. Glucocorticoids reduce inflammation around the joints and ease pain. But like most treatments, steroids have side effects. Studies have shown that they raise the risk of developing osteoporosis.
One way to study this problem is to treat laboratory mice with steroids and with various interventions meant to counteract the side effect. A key challenge is how to assess a bone's structural integrity. The gold standard, removing the bone and measuring the amount of force needed to snap it in half, can only be performed by sacrificing the animal. Standard X-ray techniques can noninvasively determine bone mineral density, but this has proven to be a poor predictor of fracture risk in humans with steroid-induced osteoporosis.
The Rochester team is developing a new technique that promises to be non-invasive, based on a technique called Raman spectroscopy. By measuring how light scatters off the materials inside bone, they have been able to calculate the relative amounts of mineral and protein matrix of intact bones. They hope to find new and better indicators of bone strength in the chemical information that Raman spectroscopy provides about both the bone mineral and collagen matrix that make up bone.Multiply that by 6 fixtures and we'll be buying 300 bulbs! If the cost per bulb averages $2 we'll end up paying an led lamp additional $600 for a grand total of $2,550 to run six incandescent lights.One of the great benefits from the low voltage Insulator range is that the budget range is still of a considerable quality and value.The term budget can often lead people to think that the cheaper alternative is going to be of a much poorer quality but that is not always the case.
"Our ultimate goal is to be able to measure the properties of a bone within an intact mouse limb," said Berger. "We hope to develop a better way to spot osteoporosis early in its onset."
The presentation, "Steroid Induced Osteoporosis Detected by Raman Spectroscopy" is at 3:15 p.m. on Monday, Oct.Designers suggest that a good cfl bulbs ambient lighting needs to have a variation of fixtures. Do not limit yourself to a single ceiling mounted fixture, which often creates shadows. Ambient lighting can be served well by fluorescent lamps.While not all current LED replacement bulbs live up to their claims, products like the Cree LR6 table lamps Downlight provide you with beautiful warm white light, an 85% energy savings over conventional incandescent bulbs and a 50,000 hour life span. 25.
Researchers at the University of Rochester in New York are developing a new way to monitor bone health and search for signs of osteoporosis, using infrared light.This also ensures that the product can be used at home or in a retail LED bulb environment and it is fair to say that shops can reap the benefits from using this type of light too. At Frontiers in Optics 2010, Jason Maher, Andrew Berger, and their colleagues will present ongoing studies of the effects of steroids on the bones of mice.
Steroids are commonly prescribed for the treatment of rheumatoid arthritis. Glucocorticoids reduce inflammation around the joints and ease pain. But like most treatments, steroids have side effects. Studies have shown that they raise the risk of developing osteoporosis.
One way to study this problem is to treat laboratory mice with steroids and with various interventions meant to counteract the side effect. A key challenge is how to assess a bone's structural integrity. The gold standard, removing the bone and measuring the amount of force needed to snap it in half, can only be performed by sacrificing the animal. Standard X-ray techniques can noninvasively determine bone mineral density, but this has proven to be a poor predictor of fracture risk in humans with steroid-induced osteoporosis.
The Rochester team is developing a new technique that promises to be non-invasive, based on a technique called Raman spectroscopy. By measuring how light scatters off the materials inside bone, they have been able to calculate the relative amounts of mineral and protein matrix of intact bones. They hope to find new and better indicators of bone strength in the chemical information that Raman spectroscopy provides about both the bone mineral and collagen matrix that make up bone.Multiply that by 6 fixtures and we'll be buying 300 bulbs! If the cost per bulb averages $2 we'll end up paying an led lamp additional $600 for a grand total of $2,550 to run six incandescent lights.One of the great benefits from the low voltage Insulator range is that the budget range is still of a considerable quality and value.The term budget can often lead people to think that the cheaper alternative is going to be of a much poorer quality but that is not always the case.
"Our ultimate goal is to be able to measure the properties of a bone within an intact mouse limb," said Berger. "We hope to develop a better way to spot osteoporosis early in its onset."
The presentation, "Steroid Induced Osteoporosis Detected by Raman Spectroscopy" is at 3:15 p.m. on Monday, Oct.Designers suggest that a good cfl bulbs ambient lighting needs to have a variation of fixtures. Do not limit yourself to a single ceiling mounted fixture, which often creates shadows. Ambient lighting can be served well by fluorescent lamps.While not all current LED replacement bulbs live up to their claims, products like the Cree LR6 table lamps Downlight provide you with beautiful warm white light, an 85% energy savings over conventional incandescent bulbs and a 50,000 hour life span. 25.
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